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Understanding Prion Strains: Evidence from Studies of the Disease Forms Affecting Humans
Prion diseases are a unique group of rare neurodegenerative disorders characterized by tissue deposition of heterogeneous aggregates of abnormally folded protease-resistant prion protein (PrP(Sc)), a broad spectrum of disease phenotypes and a variable efficiency of disease propagation in vivo. The d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520670/ https://www.ncbi.nlm.nih.gov/pubmed/30934971 http://dx.doi.org/10.3390/v11040309 |