Low CD8(+) T Cell Infiltration and High PD-L1 Expression Are Associated with Level of CD44(+)/CD133(+) Cancer Stem Cells and Predict an Unfavorable Prognosis in Pancreatic Cancer

Cancer immunotherapy targeting immune checkpoints has exhibited promising clinical outcomes in many cancers, but it offers only limited benefits for pancreatic cancer (PC). Cancer stem cells (CSCs), a minor subpopulation of cancer cells, play important roles in tumor initiation, progression, and dru...

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Detalles Bibliográficos
Autores principales: Hou, Ya-Chin, Chao, Ying-Jui, Hsieh, Min-Hua, Tung, Hui-Ling, Wang, Hao-Chen, Shan, Yan-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520688/
https://www.ncbi.nlm.nih.gov/pubmed/30991694
http://dx.doi.org/10.3390/cancers11040541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520688/
https://www.ncbi.nlm.nih.gov/pubmed/30991694
http://dx.doi.org/10.3390/cancers11040541

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