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Contingencies of UTX/KDM6A Action in Urothelial Carcinoma

The histone demethylase Ubiquitously Transcribed Tetratricopeptide Repeat Protein X-Linked (UTX/KDM6A) demethylates H3K27me2/3 at genes and enhancers and is often inactivated by mutations in urothelial carcinoma (UC). The consequences of its inactivation are however poorly understood. We have invest...

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Detalles Bibliográficos
Autores principales: Lang, Alexander, Yilmaz, Merve, Hader, Christiane, Murday, Sammy, Kunz, Xenia, Wagner, Nicholas, Wiek, Constanze, Petzsch, Patrick, Köhrer, Karl, Koch, Julian, Hoffmann, Michéle J., Greife, Annemarie, Schulz, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520694/
https://www.ncbi.nlm.nih.gov/pubmed/30987376
http://dx.doi.org/10.3390/cancers11040481