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Characterization of EIAV env Quasispecies during Long-Term Passage In Vitro: Gradual Loss of Pathogenicity

As the only widely used live lentiviral vaccine, the equine infectious anima virus (EIAV) attenuated vaccine was developed by in vitro passaging of a virulent strain for 121 generations. In our previous study, we observed that the attenuated vaccine was gradually selected under increased environment...

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Detalles Bibliográficos
Autores principales: Liu, Cong, Wang, Xue-Feng, Wang, Yan, Chen, Jie, Zhong, Zhaohua, Lin, Yuezhi, Wang, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520696/
https://www.ncbi.nlm.nih.gov/pubmed/31022927
http://dx.doi.org/10.3390/v11040380