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All the Same? The Secret Life of Prion Strains within Their Target Cells

Prions are infectious β-sheet-rich protein aggregates composed of misfolded prion protein (PrP(Sc)) that do not possess coding nucleic acid. Prions replicate by recruiting and converting normal cellular PrP(C) into infectious isoforms. In the same host species, prion strains target distinct brain re...

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Detalles Bibliográficos
Autor principal: Vorberg, Ina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520713/
https://www.ncbi.nlm.nih.gov/pubmed/30970585
http://dx.doi.org/10.3390/v11040334

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