Integrative In Vivo Drug Testing Using Gene Expression Signature and Patient-Derived Xenografts from Treatment-Refractory HER2 Positive and Triple-Negative Subtypes of Breast Cancer

Patient-derived xenografts (PDXs) are powerful tools for translational cancer research. Here, we established PDX models from different molecular subtypes of breast cancer for in vivo drug tests and compared the histopathologic features of PDX model tumors with those of patient tumors. Predictive bio...

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Detalles Bibliográficos
Autores principales: Ryu, Jin-Sun, Sim, Sung Hoon, Park, In Hae, Lee, Eun Gyeong, Lee, Eun Sook, Kim, Yun-Hee, Kwon, Youngmee, Kong, Sun-Young, Lee, Keun Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520730/
https://www.ncbi.nlm.nih.gov/pubmed/31018595
http://dx.doi.org/10.3390/cancers11040574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520730/
https://www.ncbi.nlm.nih.gov/pubmed/31018595
http://dx.doi.org/10.3390/cancers11040574

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