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Integrated Somatic and Germline Whole-Exome Sequencing Analysis in Women with Lung Cancer after a Previous Breast Cancer

Women treated for breast cancer (BC) are at risk of developing secondary tumors, such as lung cancer (LC). Since rare germline variants have been linked to multiple cancer development, we hypothesized that BC survivors might be prone to develop LC as a result of harboring rare variants. Sixty patien...

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Detalles Bibliográficos
Autores principales: Coco, Simona, Bonfiglio, Silvia, Cittaro, Davide, Vanni, Irene, Mora, Marco, Genova, Carlo, Dal Bello, Maria Giovanna, Boccardo, Simona, Alama, Angela, Rijavec, Erika, Sini, Claudio, Rossella, Valeria, Barletta, Giulia, Biello, Federica, Truini, Anna, Bruzzo, Cristina, Gallo, Maurizio, Lazarevic, Dejan, Ballestrero, Alberto, Grossi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520745/
https://www.ncbi.nlm.nih.gov/pubmed/30925779
http://dx.doi.org/10.3390/cancers11040441