Next-Generation Hedgehog/GLI Pathway Inhibitors for Cancer Therapy

The Hedgehog/Glioma-associated oncogene homolog (HH/GLI) signaling pathway regulates self-renewal of rare and highly malignant cancer stem cells (CSC), which have been shown to account for the initiation and maintenance of tumor growth as well as for drug resistance, metastatic spread and relapse. E...

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Detalles Bibliográficos
Autores principales: Peer, Elisabeth, Tesanovic, Suzana, Aberger, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520835/
https://www.ncbi.nlm.nih.gov/pubmed/30991683
http://dx.doi.org/10.3390/cancers11040538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520835/
https://www.ncbi.nlm.nih.gov/pubmed/30991683
http://dx.doi.org/10.3390/cancers11040538

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