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Total Synthesis of Mycalisine B

The first total synthesis of the marine nucleoside Mycalisine B—a naturally occurring and structurally distinct 4,5-unsaturated 7-deazapurine nucleoside—has been accomplished in 10 linear steps with 27.5% overall yield from commercially available 1,2,3,5-tetra-O-acetyl-ribose and tetracyanoethylene....

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Detalles Bibliográficos
Autores principales: Ding, Haixin, Ruan, Zhizhong, Kou, Peihao, Dong, Xiangyou, Bai, Jiang, Xiao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520845/
https://www.ncbi.nlm.nih.gov/pubmed/31013980
http://dx.doi.org/10.3390/md17040226