Cargando…

Role of Protein Kinases in Hedgehog Pathway Control and Implications for Cancer Therapy

Hedgehog (HH) signaling is an evolutionarily conserved pathway that is crucial for growth and tissue patterning during embryonic development. It is mostly quiescent in the adult, where it regulates tissue homeostasis and stem cell behavior. Aberrant reactivation of HH signaling has been associated t...

Descripción completa

Detalles Bibliográficos
Autores principales: Montagnani, Valentina, Stecca, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520855/
https://www.ncbi.nlm.nih.gov/pubmed/30934935
http://dx.doi.org/10.3390/cancers11040449