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Frequent Occurrence of NRAS and BRAF Mutations in Human Acral Naevi

Acral naevi are benign melanocytic tumors occurring at acral sites. Occasionally they can progress to become malignant tumors (melanomas). The genetics of acral naevi have not been assessed in larger studies. In our study, a large cohort of 130 acral naevi was screened for gene mutations known to be...

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Detalles Bibliográficos
Autores principales: Jansen, Philipp, Cosgarea, Ioana, Murali, Rajmohan, Möller, Inga, Sucker, Antje, Franklin, Cindy, Paschen, Annette, Zaremba, Anne, Brinker, Titus J., Stoffels, Ingo, Schadendorf, Dirk, Klode, Joachim, Hadaschik, Eva, Griewank, Klaus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520878/
https://www.ncbi.nlm.nih.gov/pubmed/30995742
http://dx.doi.org/10.3390/cancers11040546