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Purification and Biochemical Characterization of TsMS 3 and TsMS 4: Neuropeptide-Degrading Metallopeptidases in the Tityus serrulatus Venom

Although omics studies have indicated presence of proteases on the Tityus serrulatus venom (TsV), little is known about the function of these molecules. The TsV contains metalloproteases that cleave a series of human neuropeptides, including the dynorphin A (1-13) and the members of neuropeptide Y f...

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Detalles Bibliográficos
Autores principales: Cajado-Carvalho, Daniela, da Silva, Cristiane Castilho Fernandes, Kodama, Roberto Tadashi, Mariano, Douglas Oscar Ceolin, Pimenta, Daniel Carvalho, Duzzi, Bruno, Kuniyoshi, Alexandre Kazuo, Portaro, Fernanda Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520902/
https://www.ncbi.nlm.nih.gov/pubmed/30935107
http://dx.doi.org/10.3390/toxins11040194