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CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor

KRAS-driven non-small cell lung cancer (NSCLC) patients have no effective targeted treatment. In this study, we aimed to investigate targeting epidermal growth factor receptor (EGFR) as a therapeutic approach in KRAS-driven lung cancer cells. We show that ablation of EGFR significantly suppressed tu...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Song, Shanshan, Setroikromo, Rita, Chen, Siwei, Hu, Wenteng, Chen, Deng, van der Wekken, Anthonie J., Melgert, Barbro N., Timens, Wim, van den Berg, Anke, Saber, Ali, Haisma, Hidde J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520904/
https://www.ncbi.nlm.nih.gov/pubmed/30935067
http://dx.doi.org/10.3390/cancers11040455