Cargando…

CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor

KRAS-driven non-small cell lung cancer (NSCLC) patients have no effective targeted treatment. In this study, we aimed to investigate targeting epidermal growth factor receptor (EGFR) as a therapeutic approach in KRAS-driven lung cancer cells. We show that ablation of EGFR significantly suppressed tu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Bin, Song, Shanshan, Setroikromo, Rita, Chen, Siwei, Hu, Wenteng, Chen, Deng, van der Wekken, Anthonie J., Melgert, Barbro N., Timens, Wim, van den Berg, Anke, Saber, Ali, Haisma, Hidde J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520904/ https://www.ncbi.nlm.nih.gov/pubmed/30935067 http://dx.doi.org/10.3390/cancers11040455

Ejemplares similares

D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling
por: Song, Shanshan, et al.
Publicado: (2021)

Chronic Obstructive Pulmonary Disease Is Not Associated with KRAS Mutations in Non-Small Cell Lung Cancer
por: Saber, Ali, et al.
Publicado: (2016)

CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine/Chemokine Receptor Complex in Patients with AMD
por: Falk, Mads Krüger, et al.
Publicado: (2014)

Activation of the human chemokine receptor CX3CR1 regulated by cholesterol
por: Lu, Minmin, et al.
Publicado: (2022)

Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation
por: Rowinska, Zuzanna, et al.
Publicado: (2017)

PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection
por: Utari, Putri D., et al.
Publicado: (2018)

Histone Deacetylase Inhibitors Sensitize TRAIL-Induced Apoptosis in Colon Cancer Cells
por: Zhang, Baojie, et al.
Publicado: (2019)

CX3C-chemokine receptor 1 modulates cognitive dysfunction induced by sleep deprivation
por: Xin, Jiawei, et al.
Publicado: (2022)

VHH antibody targeting the chemokine receptor CX3CR1 inhibits progression of atherosclerosis
por: Low, Sarah, et al.
Publicado: (2020)

The Chemokine CX3CL1 (Fractalkine) and its Receptor CX3CR1: Occurrence and Potential Role in Osteoarthritis
por: Wojdasiewicz, Piotr, et al.
Publicado: (2014)

Mutations in EMT-Related Genes in ALK Positive Crizotinib Resistant Non-Small Cell Lung Cancers
por: Wei, Jiacong, et al.
Publicado: (2018)

Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis
por: Zheng, Jiao, et al.
Publicado: (2013)

CRISPR-mediated ablation of overexpressed EGFR in combination with sunitinib significantly suppresses renal cell carcinoma proliferation
por: Liu, Bin, et al.
Publicado: (2020)

Overall survival in advanced epidermal growth factor receptor mutated non-small cell lung cancer using different tyrosine kinase inhibitors in The Netherlands: a retrospective, nationwide registry study
por: Gijtenbeek, Rolof G.P., et al.
Publicado: (2023)

Fractalkine receptor chemokine (CX3CR1) influences on cervical and lumbar disc herniation
por: Oh, In-Soo, et al.
Publicado: (2015)

Ischemia-induced Neuronal Cell Death Is Mediated by Chemokine Receptor CX3CR1
por: Wang, Jinkun, et al.
Publicado: (2018)

Genomic Aberrations in Crizotinib Resistant Lung Adenocarcinoma Samples Identified by Transcriptome Sequencing
por: Saber, Ali, et al.
Publicado: (2016)

The chemokine receptor CX(3)CR1 is directly involved in the arrest of breast cancer cells to the skeleton
por: Jamieson-Gladney, Whitney L, et al.
Publicado: (2011)

MiRNA-101 inhibits breast cancer growth and metastasis by targeting CX chemokine receptor 7
por: Li, Jun-Tang, et al.
Publicado: (2015)

Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients
por: Bacchi, Carlos E., et al.
Publicado: (2012)

An All-In-One Transcriptome-Based Assay to Identify Therapy-Guiding Genomic Aberrations in Nonsmall Cell Lung Cancer Patients
por: Wei, Jiacong, et al.
Publicado: (2020)

The chemokine receptor CX (3) CR1 coordinates monocyte recruitment and endothelial regeneration after arterial injury
por: Getzin, Tobias, et al.
Publicado: (2017)

Interaction of Tau with the chemokine receptor, CX3CR1 and its effect on microglial activation, migration and proliferation
por: Chidambaram, Hariharakrishnan, et al.
Publicado: (2020)

Chemokines and Chemokine Receptors in Multiple Sclerosis
por: Cheng, Wenjing, et al.
Publicado: (2014)

Chemokines and their receptors in Atherosclerosis
por: van der Vorst, Emiel P. C., et al.
Publicado: (2015)

Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures
por: Käufer, Christopher, et al.
Publicado: (2018)

The Role of Chemokines and Chemokine Receptors in Diabetic Nephropathy
por: Chang, Ting-Ting, et al.
Publicado: (2020)

The role of chemokines and chemokine receptors in multiple sclerosis
por: Cui, Li-Yuan, et al.
Publicado: (2020)

Interaction between epidermal growth factor receptor and C-C motif chemokine receptor 2 in the ovulatory cascade
por: Conte, J. G., et al.
Publicado: (2023)

Association of chemokine receptor CX3CR1 V249I and T280M polymorphisms with chronic kidney disease
por: Yadav, A. K., et al.
Publicado: (2016)

CX(3)C chemokine receptor 1 deficiency modulates microglia morphology but does not affect lesion size and short-term deficits after experimental stroke
por: van der Maten, Gerlinde, et al.
Publicado: (2017)

Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5
por: Zhang, Hui, et al.
Publicado: (2021)

Extensive expansion and diversification of the chemokine gene family in zebrafish: Identification of a novel chemokine subfamily CX
por: Nomiyama, Hisayuki, et al.
Publicado: (2008)

Chemokines and Chemokine Receptors in Lymphocyte Traffic
por: Loetsacher, Pius
Publicado: (2000)

Chemokines and chemokine receptors in Behçet’s disease
por: Li, Zhan, et al.
Publicado: (2023)

CX3 chemokine receptor 1 deficiency leads to reduced dendritic complexity and delayed maturation of newborn neurons in the adult mouse hippocampus
por: Xiao, Feng, et al.
Publicado: (2015)

Cx32 exerts anti-apoptotic and pro-tumor effects via the epidermal growth factor receptor pathway in hepatocellular carcinoma
por: Xiang, Yuke, et al.
Publicado: (2019)

Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy
por: Abu El-Asrar, Ahmed M., et al.
Publicado: (2021)

The diversity of myeloid immune cells shaping wound repair and fibrosis in the lung
por: Florez‐Sampedro, Laura, et al.
Publicado: (2018)

Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient
por: Siddiqui, Imran, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vltoamci9tuaf0u81g3b52be1d