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HDAC Inhibitors Exert Anti-Myeloma Effects through Multiple Modes of Action

HDACs are critical regulators of gene expression that function through histone modification. Non-histone proteins and histones are targeted by these proteins and the inhibition of HDACs results in various biological effects. Moreover, the aberrant expression and function of these proteins is thought...

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Detalles Bibliográficos
Autores principales: Imai, Yoichi, Hirano, Mitsuhito, Kobayashi, Masayuki, Futami, Muneyoshi, Tojo, Arinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520917/
https://www.ncbi.nlm.nih.gov/pubmed/30987296
http://dx.doi.org/10.3390/cancers11040475