Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus

Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes severe disease in humans with case-fatality rates of up to 30%. There are currently very limited treatment options for SFTSV infection. We conducted a drug repurposing program by establishing a...

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Detalles Bibliográficos
Autores principales: Yuan, Shuofeng, Chan, Jasper Fuk-Woo, Ye, Zi-Wei, Wen, Lei, Tsang, Terance Gi-Wai, Cao, Jianli, Huang, Jingjing, Chan, Chris Chun-Yiu, Chik, Kenn Ka-Heng, Choi, Garnet Kwan-Yue, Cai, Jian-Piao, Yin, Feifei, Chu, Hin, Liang, Mifang, Jin, Dong-Yan, Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520937/
https://www.ncbi.nlm.nih.gov/pubmed/31027241
http://dx.doi.org/10.3390/v11040385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520937/
https://www.ncbi.nlm.nih.gov/pubmed/31027241
http://dx.doi.org/10.3390/v11040385

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