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Capsaicin Analogues Derived from n-3 Polyunsaturated Fatty Acids (PUFAs) Reduce Inflammatory Activity of Macrophages and Stimulate Insulin Secretion by β-Cells In Vitro

In this study, two capsaicin analogues, N-eicosapentaenoyl vanillylamine (EPVA) and N-docosahexaenoyl vanillylamine (DHVA), were enzymatically synthesized from their corresponding n-3 long chain polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both dietary rele...

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Detalles Bibliográficos
Autores principales: Cione, Erika, Plastina, Pierluigi, Pingitore, Attilio, Perri, Mariarita, Caroleo, Maria Cristina, Fazio, Alessia, Witkamp, Renger, Meijerink, Jocelijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520993/
https://www.ncbi.nlm.nih.gov/pubmed/31022842
http://dx.doi.org/10.3390/nu11040915