α7 Nicotinic Acetylcholine Receptor Signaling Modulates Ovine Fetal Brain Astrocytes Transcriptome in Response to Endotoxin

Neuroinflammation in utero may result in lifelong neurological disabilities. Astrocytes play a pivotal role in this process, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance neuroprotective potential of astrocytes. We hypothesized that agonism on α7...

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Detalles Bibliográficos
Autores principales: Cao, Mingju, MacDonald, James W., Liu, Hai L., Weaver, Molly, Cortes, Marina, Durosier, Lucien D., Burns, Patrick, Fecteau, Gilles, Desrochers, André, Schulkin, Jay, Antonelli, Marta C., Bernier, Raphael A., Dorschner, Michael, Bammler, Theo K., Frasch, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520997/
https://www.ncbi.nlm.nih.gov/pubmed/31143190
http://dx.doi.org/10.3389/fimmu.2019.01063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520997/
https://www.ncbi.nlm.nih.gov/pubmed/31143190
http://dx.doi.org/10.3389/fimmu.2019.01063

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