A Novel ALDH1A1 Inhibitor Targets Cells with Stem Cell Characteristics in Ovarian Cancer

A small of population of slow cycling and chemo-resistant cells referred to as cancer stem cells (CSC) have been implicated in cancer recurrence. There is emerging interest in developing targeted therapeutics to eradicate CSCs. Aldehyde-dehydrogenase (ALDH) activity was shown to be a functional mark...

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Detalles Bibliográficos
Autores principales: Nwani, Nkechiyere G., Condello, Salvatore, Wang, Yinu, Swetzig, Wendy M., Barber, Emma, Hurley, Thomas, Matei, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521036/
https://www.ncbi.nlm.nih.gov/pubmed/30965686
http://dx.doi.org/10.3390/cancers11040502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521036/
https://www.ncbi.nlm.nih.gov/pubmed/30965686
http://dx.doi.org/10.3390/cancers11040502

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