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Dopamine-Induced Ascorbate Release From Retinal Neurons Involves Glutamate Release, Activation of AMPA/Kainate Receptors and Downstream Signaling Pathways

Ascorbate, the reduced form of Vitamin C, is one of the most abundant and important low-molecular weight antioxidants in living tissues. Most animals synthesize vitamin C, but some primates, including humans, have lost this capacity due to disruption in L-gulono-gamma-lactone oxidase gene. Because o...

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Detalles Bibliográficos
Autores principales: Portugal, Camila Cabral, da Encarnação, Thaísa Godinho, Domith, Ivan, dos Santos Rodrigues, Alexandre, de Oliveira, Nádia Almeida, Socodato, Renato, Paes-de-Carvalho, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521073/
https://www.ncbi.nlm.nih.gov/pubmed/31143097
http://dx.doi.org/10.3389/fnins.2019.00453