Assessment of a High Sensitivity Method for Identification of IDH1 R132x Mutations in Tumors and Plasma of Intrahepatic Cholangiocarcinoma Patients

Hotspot codon 132 mutations (R132xIDH1m) are frequent in intrahepatic cholangiocarcinoma (ICC), are druggable by anti-IDH1m agents, and could represent a marker of disease progression. Developing an assay to identify R132xIDH1m would provide a useful tool to select patients benefitting from targeted...

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Detalles Bibliográficos
Autores principales: Peraldo-Neia, Caterina, Scatolini, Maria, Grosso, Enrico, Lombardi, Pasquale, Filippi, Roberto, Raggi, Chiara, Marchiò, Caterina, Cavalloni, Giuliana, Aglietta, Massimo, Leone, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521091/
https://www.ncbi.nlm.nih.gov/pubmed/30935002
http://dx.doi.org/10.3390/cancers11040454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521091/
https://www.ncbi.nlm.nih.gov/pubmed/30935002
http://dx.doi.org/10.3390/cancers11040454

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