Sequential Blockade of PD-1 and PD-L1 Causes Fulminant Cardiotoxicity—From Case Report to Mouse Model Validation

The combined administration of programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors might be considered as a treatment for poorly responsive cancer. We report a patient with brain metastatic lung adenocarcinoma in whom fatal myocarditis developed after sequential use...

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Detalles Bibliográficos
Autores principales: Liu, Shin-Yi, Huang, Wen-Chien, Yeh, Hung-I, Ko, Chun-Chuan, Shieh, Hui-Ru, Hung, Chung-Lieh, Chen, Tung-Ying, Chen, Yu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521128/
https://www.ncbi.nlm.nih.gov/pubmed/31022941
http://dx.doi.org/10.3390/cancers11040580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521128/
https://www.ncbi.nlm.nih.gov/pubmed/31022941
http://dx.doi.org/10.3390/cancers11040580

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