Statins Do Not Directly Inhibit the Activity of Major Epigenetic Modifying Enzymes

The potential anticancer effects of statins—a widely used class of cholesterol lowering drugs—has generated significant interest, as has the use of epigenetic modifying drugs such as HDAC and DNMT inhibitors. We set out to investigate the effect of statin drugs on epigenetic modifications in multipl...

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Detalles Bibliográficos
Autores principales: Bridgeman, Stephanie, Northrop, Wendy, Ellison, Gaewyn, Sabapathy, Thiru, Melton, Phillip E., Newsholme, Philip, Mamotte, Cyril D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521159/
https://www.ncbi.nlm.nih.gov/pubmed/30974899
http://dx.doi.org/10.3390/cancers11040516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521159/
https://www.ncbi.nlm.nih.gov/pubmed/30974899
http://dx.doi.org/10.3390/cancers11040516

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