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Improving Payload Capacity and Anti-Tumor Efficacy of Mesenchymal Stem Cells Using TAT Peptide Functionalized Polymeric Nanoparticles

Mesenchymal stem cells (MSCs) accumulate specifically in both primary tumors and metastases following systemic administration. However, the poor payload capacity of MSCs limits their use in small molecule drug delivery. To improve drug payload in MSCs, we explored polymeric nanoparticles that were f...

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Detalles Bibliográficos
Autores principales: Moku, Gopikrishna, Layek, Buddhadev, Trautman, Lana, Putnam, Samuel, Panyam, Jayanth, Prabha, Swayam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521160/
https://www.ncbi.nlm.nih.gov/pubmed/30959908
http://dx.doi.org/10.3390/cancers11040491