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Improving Payload Capacity and Anti-Tumor Efficacy of Mesenchymal Stem Cells Using TAT Peptide Functionalized Polymeric Nanoparticles
Mesenchymal stem cells (MSCs) accumulate specifically in both primary tumors and metastases following systemic administration. However, the poor payload capacity of MSCs limits their use in small molecule drug delivery. To improve drug payload in MSCs, we explored polymeric nanoparticles that were f...
Autores principales: | Moku, Gopikrishna, Layek, Buddhadev, Trautman, Lana, Putnam, Samuel, Panyam, Jayanth, Prabha, Swayam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521160/ https://www.ncbi.nlm.nih.gov/pubmed/30959908 http://dx.doi.org/10.3390/cancers11040491 |
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