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Efficacy of a Selective Binder of α(V)β(3) Integrin Linked to the Tyrosine Kinase Inhibitor Sunitinib in Ovarian Carcinoma Preclinical Models

Ovarian carcinoma, the most lethal gynecological cancer, is characterized by late diagnosis, with drug resistance limiting the efficacy of platinum-based therapy. Since some integrins are upregulated in cancer, including ovarian carcinoma, they represent a potential target for drug delivery. Recepto...

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Detalles Bibliográficos
Autores principales: Sartori, Andrea, Corno, Cristina, De Cesare, Michelandrea, Scanziani, Eugenio, Minoli, Lucia, Battistini, Lucia, Zanardi, Franca, Perego, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521192/
https://www.ncbi.nlm.nih.gov/pubmed/31013908
http://dx.doi.org/10.3390/cancers11040531