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Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders

The radial spatial positioning of individual gene loci within interphase nuclei has been associated with up- and downregulation of their expression. In cancer, the genome organization may become disturbed due to chromosomal abnormalities, such as translocations or deletions, resulting in the reposit...

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Detalles Bibliográficos
Autores principales: Federico, Concetta, Owoka, Temitayo, Ragusa, Denise, Sturiale, Valentina, Caponnetto, Domenica, Leotta, Claudia Giovanna, Bruno, Francesca, Foster, Helen A., Rigamonti, Silvia, Giudici, Giovanni, Cazzaniga, Giovanni, Bridger, Joanna M., Sisu, Cristina, Saccone, Salvatore, Tosi, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521283/
https://www.ncbi.nlm.nih.gov/pubmed/31027247
http://dx.doi.org/10.3390/cancers11040585