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ROS Production and Distribution: A New Paradigm to Explain the Differential Effects of X-ray and Carbon Ion Irradiation on Cancer Stem Cell Migration and Invasion

Although conventional radiotherapy promotes the migration/invasion of cancer stem cells (CSCs) under normoxia, carbon ion (C-ion) irradiation actually decreases these processes. Unraveling the mechanisms of this discrepancy, particularly under the hypoxic conditions that pertain in niches where CSCs...

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Detalles Bibliográficos
Autores principales: Wozny, Anne-Sophie, Vares, Guillaume, Alphonse, Gersende, Lauret, Alexandra, Monini, Caterina, Magné, Nicolas, Cuerq, Charlotte, Fujimori, Akira, Monboisse, Jean-Claude, Beuve, Michael, Nakajima, Tetsuo, Rodriguez-Lafrasse, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521340/
https://www.ncbi.nlm.nih.gov/pubmed/30987217
http://dx.doi.org/10.3390/cancers11040468