Addressing confounding artifacts in reconstruction of gene co-expression networks

Gene co-expression networks capture biological relationships between genes and are important tools in predicting gene function and understanding disease mechanisms. We show that technical and biological artifacts in gene expression data confound commonly used network reconstruction algorithms. We de...

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Detalles Bibliográficos
Autores principales: Parsana, Princy, Ruberman, Claire, Jaffe, Andrew E., Schatz, Michael C., Battle, Alexis, Leek, Jeffrey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521369/
https://www.ncbi.nlm.nih.gov/pubmed/31097038
http://dx.doi.org/10.1186/s13059-019-1700-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521369/
https://www.ncbi.nlm.nih.gov/pubmed/31097038
http://dx.doi.org/10.1186/s13059-019-1700-9

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