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Addressing confounding artifacts in reconstruction of gene co-expression networks
Gene co-expression networks capture biological relationships between genes and are important tools in predicting gene function and understanding disease mechanisms. We show that technical and biological artifacts in gene expression data confound commonly used network reconstruction algorithms. We de...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521369/ https://www.ncbi.nlm.nih.gov/pubmed/31097038 http://dx.doi.org/10.1186/s13059-019-1700-9 |