Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells

BACKGROUND: Bursopentin (BP5) is a multifunctional pentapeptide found in the chicken bursa of Fabricius. Recent study indicated that BP5 significantly stimulates expression of p53 protein in colon cancer HCT116 cells. However, the effects and underlying mechanisms of BP5 on HCT116 cell proliferation...

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Detalles Bibliográficos
Autores principales: Li, Jing, Li, Tian-xiang, Ma, Yao, Zhang, Yong, Li, De-yuan, Xu, Hai-rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521404/
https://www.ncbi.nlm.nih.gov/pubmed/31123429
http://dx.doi.org/10.1186/s12935-019-0849-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521404/
https://www.ncbi.nlm.nih.gov/pubmed/31123429
http://dx.doi.org/10.1186/s12935-019-0849-3

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