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Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells
BACKGROUND: Bursopentin (BP5) is a multifunctional pentapeptide found in the chicken bursa of Fabricius. Recent study indicated that BP5 significantly stimulates expression of p53 protein in colon cancer HCT116 cells. However, the effects and underlying mechanisms of BP5 on HCT116 cell proliferation...
Autores principales: | Li, Jing, Li, Tian-xiang, Ma, Yao, Zhang, Yong, Li, De-yuan, Xu, Hai-rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521404/ https://www.ncbi.nlm.nih.gov/pubmed/31123429 http://dx.doi.org/10.1186/s12935-019-0849-3 |
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