The need for mathematical modelling of spatial drug distribution within the brain

The blood brain barrier (BBB) is the main barrier that separates the blood from the brain. Because of the BBB, the drug concentration-time profile in the brain may be substantially different from that in the blood. Within the brain, the drug is subject to distributional and elimination processes: di...

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Detalles Bibliográficos
Autores principales: Vendel, Esmée, Rottschäfer, Vivi, de Lange, Elizabeth C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521438/
https://www.ncbi.nlm.nih.gov/pubmed/31092261
http://dx.doi.org/10.1186/s12987-019-0133-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521438/
https://www.ncbi.nlm.nih.gov/pubmed/31092261
http://dx.doi.org/10.1186/s12987-019-0133-x

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