Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in the Conventional Pig as Potential Pediatric Animal Model

Pediatric drug development, especially in disease areas that only affect children, can be stimulated by using juvenile animal models not only for general safety studies, but also to gain knowledge on the pharmacokinetic and pharmacodynamic properties of the drug. Recently, the conventional growing p...

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Detalles Bibliográficos
Autores principales: Millecam, Joske, van Bergen, Thomas, Schauvliege, Stijn, Antonissen, Gunther, Martens, Ann, Chiers, Koen, Gehring, Ronette, Gasthuys, Elke, Vande Walle, Johan, Croubels, Siska, Devreese, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521589/
https://www.ncbi.nlm.nih.gov/pubmed/31143123
http://dx.doi.org/10.3389/fphar.2019.00505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521589/
https://www.ncbi.nlm.nih.gov/pubmed/31143123
http://dx.doi.org/10.3389/fphar.2019.00505

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