Cargando…

Generation of Human CRY1 and CRY2 Knockout Cells Using Duplex CRISPR/Cas9 Technology

Circadian clocks are endogenous oscillators essential for orchestrating daily rhythms in physiology, metabolism and behavior. While mouse models have been instrumental to elucidate the molecular mechanism of circadian rhythm generation, our knowledge about the molecular makeup of circadian oscillato...

Descripción completa

Detalles Bibliográficos
Autores principales: Börding, Teresa, Abdo, Ashraf N., Maier, Bert, Gabriel, Christian, Kramer, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521593/
https://www.ncbi.nlm.nih.gov/pubmed/31143130
http://dx.doi.org/10.3389/fphys.2019.00577