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Demonstration of protein cooperativity mediated by RNA structure using the human protein PUM2
Posttranslational gene regulation requires a complex network of RNA–protein interactions. Cooperativity, which tunes response sensitivities, originates from protein–protein interactions in many systems. For RNA-binding proteins, cooperativity can also be mediated through RNA structure. RNA structura...
Autores principales: | Becker, Winston R., Jarmoskaite, Inga, Vaidyanathan, Pavanapuresan P., Greenleaf, William J., Herschlag, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521599/ https://www.ncbi.nlm.nih.gov/pubmed/30914482 http://dx.doi.org/10.1261/rna.068585.118 |
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