Analysis of differential gene expression and alternative splicing is significantly influenced by choice of reference genome

RNA-seq analysis has enabled the evaluation of transcriptional changes in many species including nonmodel organisms. However, in most species only a single reference genome is available and RNA-seq reads from highly divergent varieties are typically aligned to this reference. Here, we quantify the i...

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Detalles Bibliográficos
Autores principales: Slabaugh, Erin, Desai, Jigar S., Sartor, Ryan C., Lawas, Lovely Mae F., Jagadish, S.V. Krishna, Doherty, Colleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521602/
https://www.ncbi.nlm.nih.gov/pubmed/30872414
http://dx.doi.org/10.1261/rna.070227.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521602/
https://www.ncbi.nlm.nih.gov/pubmed/30872414
http://dx.doi.org/10.1261/rna.070227.118

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