Structural insights into nanoRNA degradation by human Rexo2

Human RNA exoribonuclease 2 (Rexo2) is an evolutionarily conserved 3′-to-5′ DEDDh-family exonuclease located primarily in mitochondria. Rexo2 degrades small RNA oligonucleotides of <5 nucleotides (nanoRNA) in a way similar to Escherichia coli Oligoribonuclease (ORN), suggesting that it plays a ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Chu, Lee-Ya, Agrawal, Sashank, Chen, Yi-Ping, Yang, Wei-Zen, Yuan, Hanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521605/
https://www.ncbi.nlm.nih.gov/pubmed/30926754
http://dx.doi.org/10.1261/rna.070557.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521605/
https://www.ncbi.nlm.nih.gov/pubmed/30926754
http://dx.doi.org/10.1261/rna.070557.119

Ejemplares similares