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DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

Autophagy can protect cancer cells from acute starvation and enhance resistance to chemotherapy. Previously, we reported that autophagy plays a critical role in the survival of dormant, drug resistant ovarian cancer cells using human xenograft models and correlated the up-regulation of autophagy and...

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Detalles Bibliográficos
Autores principales: Sutton, Margie N., Huang, Gilbert Y., Liang, Xiaowen, Sharma, Rajesh, Reger, Albert S., Mao, Weiqun, Pang, Lan, Rask, Philip J., Lee, Kwangkook, Gray, Joshua P., Hurwitz, Amy M., Palzkill, Timothy, Millward, Steven W., Kim, Choel, Lu, Zhen, Bast, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521623/
https://www.ncbi.nlm.nih.gov/pubmed/31003488
http://dx.doi.org/10.3390/cancers11040557