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Nitro-Heterocyclic compounds induce apoptosis-like effects in Leishmania (L). amazonensis promastigotes

BACKGROUND: Three drugs - pentavalent antimonials, amphotericin B and pentamidine - are currently used for leishmaniasis treatment. They are administered for long periods, only parenterally, and have high cardiac, renal and hepatic toxicities. Therefore, the investigation of new compounds is require...

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Detalles Bibliográficos
Autores principales: Mendonça, Daiane Barros Dias, Silva, Renata Ellen Costa, Palace-Berl, Fanny, Takakura, Cleusa FH, Soares, Sandra Regina C, Braz, Lucia Maria Almeida, Tavares, Leoberto Costa, Lindoso, Jose Angelo Lauletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521708/
https://www.ncbi.nlm.nih.gov/pubmed/31130997
http://dx.doi.org/10.1590/1678-9199-JVATITD-1444-18