A Single-Subject Method to Detect Pathways Enriched With Alternatively Spliced Genes

RNA-Sequencing data offers an opportunity to enable precision medicine, but most methods rely on gene expression alone. To date, no methodology exists to identify and interpret alternative splicing patterns within pathways for an individual patient. This study develops methodology and conducts compu...

Descripción completa

Detalles Bibliográficos
Autores principales: Schissler, Alfred Grant, Aberasturi, Dillon, Kenost, Colleen, Lussier, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521780/
https://www.ncbi.nlm.nih.gov/pubmed/31143202
http://dx.doi.org/10.3389/fgene.2019.00414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521780/
https://www.ncbi.nlm.nih.gov/pubmed/31143202
http://dx.doi.org/10.3389/fgene.2019.00414

Ejemplares similares