ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore

Permeability transition (PT) is an increase in mitochondrial inner membrane permeability that can lead to a disruption of mitochondrial function and cell death. PT is responsible for tissue damage in stroke and myocardial infarction. It is caused by the opening of a large conductance (~1.5 nS) chann...

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Detalles Bibliográficos
Autores principales: Neginskaya, Maria A., Solesio, Maria E., Berezhnaya, Elena V., Amodeo, Giuseppe F., Mnatsakanyan, Nelli, Jonas, Elizabeth A., Pavlov, Evgeny V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521848/
https://www.ncbi.nlm.nih.gov/pubmed/30605668
http://dx.doi.org/10.1016/j.celrep.2018.12.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521848/
https://www.ncbi.nlm.nih.gov/pubmed/30605668
http://dx.doi.org/10.1016/j.celrep.2018.12.033

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