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ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore
Permeability transition (PT) is an increase in mitochondrial inner membrane permeability that can lead to a disruption of mitochondrial function and cell death. PT is responsible for tissue damage in stroke and myocardial infarction. It is caused by the opening of a large conductance (~1.5 nS) chann...
Autores principales: | Neginskaya, Maria A., Solesio, Maria E., Berezhnaya, Elena V., Amodeo, Giuseppe F., Mnatsakanyan, Nelli, Jonas, Elizabeth A., Pavlov, Evgeny V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521848/ https://www.ncbi.nlm.nih.gov/pubmed/30605668 http://dx.doi.org/10.1016/j.celrep.2018.12.033 |
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