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Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca(2+) Channel Ca(2+) Spike Propagation to the Soma
Long-term information storage in the brain requires continual modification of the neuronal transcriptome. Synaptic inputs located hundreds of micrometers from the nucleus can regulate gene transcription, requiring high-fidelity, long-range signaling from synapses in dendrites to the nucleus in the c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521872/ https://www.ncbi.nlm.nih.gov/pubmed/30917310 http://dx.doi.org/10.1016/j.celrep.2019.03.005 |