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Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis

Endothelial cells (ECs) require glycolysis for proliferation and migration during angiogenesis; however, the necessity for the mitochondrial respiratory chain during angiogenesis is not known. Here we report that inhibition of respiratory chain complex III impairs proliferation, but not migration of...

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Detalles Bibliográficos
Autores principales: Diebold, Lauren P., Gil, Hyea Jin, Gao, Peng, Martinez, Carlos A., Weinberg, Samuel E., Chandel, Navdeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521885/
https://www.ncbi.nlm.nih.gov/pubmed/31106291
http://dx.doi.org/10.1038/s42255-018-0011-x