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Icariin enhances the chemosensitivity of cisplatin‑resistant ovarian cancer cells by suppressing autophagy via activation of the AKT/mTOR/ATG5 pathway

Icariin is a flavonoid derived from Epimedium sagittatum, and has a wide range of biological and pharmacological effects; however, little is known regarding its effect on drug-resistant ovarian cancer and the signal transduction pathways underlying the regulation of apoptosis and autophagy. The pres...

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Detalles Bibliográficos
Autores principales: Jiang, Shaoyan, Chang, Hong, Deng, Shaojie, Fan, Danyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521925/
https://www.ncbi.nlm.nih.gov/pubmed/31081049
http://dx.doi.org/10.3892/ijo.2019.4785