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Simvastatin delays castration-resistant prostate cancer metastasis and androgen receptor antagonist resistance by regulating the expression of caveolin-1
The failure of androgen deprivation therapy in prostate cancer treatment mainly results from drug resistance to androgen receptor antagonists. Although an aberrant caveolin-1 (Cav-1) expression has been reported in multiple tumor cell lines, it is unknown whether it is responsible for the progressio...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521936/ https://www.ncbi.nlm.nih.gov/pubmed/31081050 http://dx.doi.org/10.3892/ijo.2019.4774 |