Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy

The transcription factor Oct1/Pou2f1 promotes poised gene expression states, mitotic stability, glycolytic metabolism and other characteristics of stem cell potency. To determine the effect of Oct1 loss on stem cell maintenance and malignancy, we deleted Oct1 in two different mouse gut stem cell com...

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Detalles Bibliográficos
Autores principales: Vázquez-Arreguín, Karina, Bensard, Claire, Schell, John C., Swanson, Eric, Chen, Xinjian, Rutter, Jared, Tantin, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522070/
https://www.ncbi.nlm.nih.gov/pubmed/31059499
http://dx.doi.org/10.1371/journal.pgen.1007687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522070/
https://www.ncbi.nlm.nih.gov/pubmed/31059499
http://dx.doi.org/10.1371/journal.pgen.1007687

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