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Fast and robust deconvolution of tumor infiltrating lymphocyte from expression profiles using least trimmed squares

Gene-expression deconvolution is used to quantify different types of cells in a mixed population. It provides a highly promising solution to rapidly characterize the tumor-infiltrating immune landscape and identify cold cancers. However, a major challenge is that gene-expression data are frequently...

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Detalles Bibliográficos
Autores principales: Hao, Yuning, Yan, Ming, Heath, Blake R., Lei, Yu L., Xie, Yuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522071/
https://www.ncbi.nlm.nih.gov/pubmed/31059559
http://dx.doi.org/10.1371/journal.pcbi.1006976