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Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

BACKGROUND: The early life environment may influence susceptibility to obesity and metabolic disease in later life through epigenetic processes. SLC6A4 is an important mediator of serotonin bioavailability, and has a key role in energy balance. We tested the hypothesis that methylation of the SLC6A4...

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Detalles Bibliográficos
Autores principales: Lillycrop, Karen A., Garratt, Emma S., Titcombe, Philip, Melton, Phillip E., Murray, Robert J. S., Barton, Sheila J., Clarke-Harris, Rebecca, Costello, Paula M., Holbrook, Joanna D., Hopkins, James C., Childs, Caroline E., Paras-Chavez, Carolina, Calder, Philip C., Mori, Trevor A., Beilin, Lawrie, Burdge, Graham C., Gluckman, Peter D., Inskip, Hazel M., Harvey, Nicholas C., Hanson, Mark A., Huang, Rae-Chi, Cooper, Cyrus, Godfrey, Keith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522375/
https://www.ncbi.nlm.nih.gov/pubmed/30622309
http://dx.doi.org/10.1038/s41366-018-0254-3